Highlights
The VK 8000 automates the tedious task of manually pulling samples. The sampling station can be configured with new testers or retrofitted to older models (Varian's or other manufacturer’s). It is flexible enough to sample up to ten time points on a single tray (or twenty when two programs are linked). Media replacement is also possible. Offered with a choice of Peristaltic or Syringe Pumps, it can even incorporate a filter changing option.
The VK 8000 integrates all Varian 6- to 8-spindle dissolution stations, as well as the BIO-DIS Extended Release Tester. The system includes the VK 8000 base station, Peristaltic Pump (standard) for sample transfer, autocalibration module for volume accuracy and automated sampling manifold for use with Varian dissolution systems (the BIO-DIS does not require a motorized manifold).
Vial Piercing Capability
Because the VK 8000 can pierce septa, you do not have to worry about evaporation distorting your results. The unique 2-barrel needle design eliminates overpressurizing of the vial during filling. Overpressurized vials lead to reproducibility problems in autosamplers.
Automatic Calibration
The patented autocalibration block is used in conjunction with the Peristaltic Pump to ensure accurate collection volume. Calibration is as easy as pressing the calibration key. The volume removed is based on the time each individual valve is left open. The accuracy is independent of volume differences in the various tubing connections.
Motorized Manifold
The motorized manifold raises and lowers sampling probes to the USP sampling location. This corrects the inaccuracy associated with the manual positioning of a hand-held syringe. There are no stationary probes to change the hydrodynamics in the vessel. If you plan to use a vessel other than the 900 mL, please bring this to our attention. We will modify the sampling manifold so the sampling cannulas will be located in the correct sampling location.
Media Replacement
The VK 8000, when used in conjunction with a Peristaltic Pump or Syringe Pump, can be upgraded to include a media replacement option. This feature allows you the programming flexibility to return an equal volume of fresh, preheated media to each dissolution vessel.
Simplified Control
The VK 8000 controls the operation of the Varian dissolution tester. All operating parameters, including those of the dissolution apparatus, can be entered using the VK 8000 keypad.
Sealed Switch-type Keypad
A fully functional keyboard has been incorporated into the VK 8000 for the entry of methods and information. The control keys along the bottom row provide programming, calibration and self-cleaning functions in addition to manual control.
Automatic Documentation
The Report Center II printer lets you print everything from system calibration verification to comprehensive test data even when the unit is unattended. Print full batch information downloaded from the dissolution testing station—including unit ID number; operating temperature; bath temperature; elapsed time; test length; RPM; sampling time points; and depending on the model and configuration of the tester, vessel temperature and dosage delivery time.
