Packed Bed: Mixed-Mode
Bond Elut Certify II
Bond Elut Certify II was developed specifically for the rapid and effective extraction of acidic drugs and metabolites from urine and other biological matrices. Certify II is a mixed-mode cartridge packed with non-polar C8 and strong anion exchanger SAX. It has been optimized for extraction of acidic drugs such as 11-nor-delta-9-tetrahydrocannabinol-9- carboxylic acid, salicylic acid, ibuprofen, acetaminophen, and other compounds possessing both non-polar and anionic character.
|
| Description of Base Silica: |
40 μm/120 μm irregular acid washed silica, |
|
60 Angstrom mean porosity |
| Bonded functional group: |
Mixed-mode sorbent bed: octyl and quaternary amine (SAX) |
| Endcapped: |
No |
| Typical percent carbon loading: |
8.6% |
| Primary retention mechanism: |
Bi-model non-polar and strong anion exchange |
| Typical sample types: |
Urine, biological fluids |
| Illustrative extractions from |
| Applications Bibliography: |
THC and metabolite/Biological fluids, M2268, |
|
Barbiturates/Biological fluids, M1833 |
|
request a copy of the Certify Methods Manual |
Amobarbital, butabarbital, pentobarbital, phenobarbital, secobarbital, and methaqualone spiked into 5 ml blank urine at concentrations of 40 ng/ml, extracted with Bond Elut Certify II. |
 |
|
